动脉粥样硬化研究室
王绿娅 研究员
研究方向:主要研究方向:脂代谢异常与动脉粥样硬化发病机制研究
主持课题:
(1)国家自然科学基金项目《脂代谢中微效多基因协同作用致遗传性高胆固醇血症的机制研究》(编号:81471098,起至年月:2015.1-2018.12)。
(2)国家自然科学基金项目《基于3号和21号染色体区域的家族性高胆固醇血症新致病基因发掘与验证》(编号:81170810,起至年月:2012.1-2015.12);
(3)北京市中医局重点学科分题: 血脂康对动脉硬化及合并糖耐量异常患者胆固醇代谢标志物影响的研究(起至年月:2011.1-2014.12 )。
近五年发表SCI文章:
Wang H, Xu S, Sun L, Pan X, Yang S, Wang L. Functional characterization of two low-density lipoprotein receptor gene mutations in twoChinese patients with familial hypercholesterolemia.PLoS One. 2014 Mar 26;9(3):e92703.
Wu WF, Sun LY, Pan XD, Yang SW, Wang LY*. Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia. PLoS One. 2014 Apr 10;9(4):e94697. Li YH, Jiang L, Jia ZR, Xin W, Yang SW, Yang Q, Wang LY*. A meta-analysis of red yeast rice: an effective and relatively safe alternative approach for dyslipidemia. PLoS ONE, 2014, 9(6): e98611.
Zhang T, Wu WF, Liu Y, Wang QH, Wang LY*, Mi SH.Change in cholesterol absorption and synthesis markers in patients with coronary heart disease after combination therapy with simvastatin plus ezetimibe.Chin Med J (Engl). 2013,126(9):1618-1623
Wu WF, Wang QH, Zhang T, Mi SH, Liu Y, Wang LY*. Gas chromatography analysis of serum cholesterol synthesis and absorption markers used to predict the efficacy of simvastatin in patients with coronary heart disease. Clin Biochem. 2013;46(12):993-998.
Wang X, Li X, Zhang YB, Zhang F, Sun L, Lin J, Wang DM, Wang LY. Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci onchromosomes 3q25-26 and 21q22. PLoS One. 2011;6(10):e24838.
联系方式:E-mail:wangluya@126.com
电话:010-64456436