Deputy Director of Beijing Institute of Heart, Lung and Blood Vessel Diseases

一、Research Interest

Research Interests: Molecular etiology of CVD, and the mechanisms of cardiovascular pathological remodeling.

二、Principal Investigator and Participate Project in 2020

As a principal investigator, Prof. Du directs key projects “Studies on the mechanism of interaction between inflammatory micro-environment and smooth muscle cells in aortic dissection” (2021/01-2024/12) from the National Natural Fund, and the role of interaction network between nucleic acid small molecules and arachidonic acid metabolic small molecules in pathological cardiac remodeling from the National Natural Fund (2018/01-2022/12), and translational research in aortic aneurysm disease (2018/01-2020/12) and Genetic basis of calcified aortic stenosis in European and Asian populations (2019/01-2021/12).

三、SCI papers published in 2020

1. Li Y# , Gao S# , Han Y# , Song L, Kong Y, Jiao Y, Huang S, Du J*, Li YL*. Variants of Focal Adhesion Scaffold Genes Cause Thoracic Aortic Aneurysm. Circ Res. 2020 Oct 23. (IF= 14.467)

2. Zhang CC, Cheng NN, Qiao BK, Zhang F, Wu J, Liu C, Li YL, Du J*. Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration.J Cachexia Sarcopenia Muscle. 2020 Oct;11(5):1291-1305.(IF=9.802)

3. Yang XY, Du XY, Ma K, Li GQ, Liu ZH, Rong W, Miao HT, Zhu FL, Cui QH, Wu SW, Li YL*, Du J*.Circulating miRNAs Related to Long-term Adverse Cardiovascular Events in STEMI Patients: A Nested CaseControl Study. Can J Cardiol. 2020 Mar 20;S0828-282X(20)30273-7. (IF=5)

4. Yixin Zhang, Yuan Wang, Bingbing Ke, Jie Du*. TMAO: how gut microbiota contributes to heart failure. Translational research. S1931-5244(20)30203-6 doi: 10.1016/j.trsl.2020.08.007.

5. Cheng N, Liu C, Li Y, Gao S, Han YC, Wang X, Du J*, Zhang C*. MicroRNA-223-3p promotes skeletal muscle regeneration by regulating inflammation in mice. J Biol Chem. 2020 Jul 24;295(30):10212-10223.

6. Zhang C, Cheng N, Qiao B, Zhang F, Wu J, Liu C, Li Y, Du J*. Age-related decline of IFN gamma responses in macrophage impairs satellite cell proliferation and regeneration. J Cachexia Sarcopenia Muscle, 2020.

7. Qiao B, † Nie JJ, † Shao Y, Li Y, Zhang C, Hao W, Li S, Chen D, Yu B, Li HH, Xu FJ, Du J.Functional Nanocomplexes with Vascular Endothelial Growth Factor A/C Isoforms Improve Collateral Circulation and Cardiac Function. Small. 2020 Jan;16(4):e1905925.

8. Exaggerated Autophagy in Stanford Type A Aortic Dissection: A Transcriptome Pilot Analysis of Human Ascending Aortic Tissues. Zeyi Zhou, Yan Liu , Xiyu Zhu , Xinlong Tang , Yali Wang, Junxia Wang, Can Xu , Dongjin Wang , Jie Du* , Qing Zhou*. Genes (Basel). 2020;11(10):1187. (IF=3.759)

9. Effects of Extracellular Matrix Softening on Vascular Smooth Muscle Cell Dysfunction. Shao Y, Li G, Huang S, Li Z, Qiao B, Chen D, Li Y, Liu H*, Du J*, Li P*. Cardiovasc Toxicol. 2020; 20 (6):548-556. (IF=2.284)

10.Lipocalin-2 Predicts Long-Term Outcome of Normotensive Patients with Acute Pulmonary Embolism. Yu H, Liu Z, Lu J, Yang X, Yan XX, Mi Y, Hua L, Li Y, Jing ZC, Du J. Cardiovasc Toxicol. 2020; 20(2):101-110. (IF=2.284)

Address

E-mail: jiedu@ccmu.edu.cn

Tel: 010-64456030