Vascular Biology Laboratory
Yulin Li, Professor
一、Research Interests
Molecular etiology of CVD, and the mechanisms of cardiovascular pathological remodeling.
二、Principal Investigator and Participate Project in 2020
Principal Investigator:
1. S100a8/9 promotes Myocardial ischemia reperfusion injury through regulating mitochondrial complex I activity (81770245, 2018-01-2021.12);
2. Fibroblast-specific ATF3 protects against myocardial Ischemia/Reperfusion as a hub of inhibiting inflammation (81970215, 2020-01-2023.12).
三、SCI papers published in 2020
1. Li Y# , Gao S# , Han Y# , Song L, Kong Y, Jiao Y, Huang S, Du J*, Li YL*. Variants of Focal Adhesion Scaffold Genes Cause Thoracic Aortic Aneurysm. Circ Res. 2020 Oct 23. ( 共同通讯作者 )(IF= 14.467)
2. Zhang CC, Cheng NN, Qiao BK, Zhang F, Wu J, Liu C, Li YL, Du J. Age-related decline of inter feron-gamma responses in macrophage impairs satellite cell proliferation and regeneration. J Cachexia Sarcopenia Muscle. 2020 Oct;11(5):1291-1305.(IF=9.802)
3. Guo HC# , Ma K# , Hao WJ, Jiao Y, Li P, Chen J, Xu C, Xu FJ, Wayne Bond Lay, Du J, Ma XL, Li YL. Mir15a/mir16-1 cluster and its novel targeting molecules negatively regulate cardiac hyper trophy. Clin Transl Med. Accepted. doi:10.1002/ctm2.242.( 通讯作者 )(IF=7.919)
4. Yang XY, Du XY, Ma K, Li GQ, Liu ZH, Rong W, Miao HT, Zhu FL, Cui QH, Wu SW, Li YL*, Du J*. Cir culating miRNAs Related to Long-term Adverse Cardiovascular Events in STEMI Patients: A Nested CaseControl Study. Can J Cardiol. 2020 Mar 20;S0828-282X(20)30273-7. ( 共同通讯作者 )(IF=5)
注：# 共同一作; * 共同通讯作者
四、Patent submitted in 2020
Patent name: Administration of Angiotensin II to improve the cardiac delivery efficiency of macro-molecular drugs or drug carriers
Patent number: 201610817404.9
Address
E-mail: lyllyl_1111@163.com
Tel: 010-64456030
