Atherosclerosis Research Center
Wang Lu-Ya, Research Fellow, Doctoral Supervisor
Research Interests: Abnormal lipid metabolism; Pathogenesis of atherosclerosis.
Principal Investigator
· “Pathogenic mechanism of lipid metabolism in polygene hereditary hypercholesterolemia”. Funded by the National Natural Science Fund Project (81471098). Support period: 01/2015–12/2018.
· “Discover and validate the new pathogenic genes in 3 and 21 chromosome regions of familial hypercholesterolemia”. Funded by the National Natural Science Fund Project (81170810). Support period: 01/2012–12/2015.
· “Influence of cholesterol metabolism markers in patients with arteriosclerosis and impaired glucose tolerance”. Funded by the Key Subject Topic of Beijing Traditional Chinese Medicine Bureau. Support period: 01/2011–12/2014.
SCI papers published in the past five years:
1. Wang H, Xu S, Sun L, Pan X, Yang S, Wang L. Functional characterization of two low-density lipoprotein receptor gene mutations in twoChinese patients with familial hypercholesterolemia.PLoS One. 2014 Mar 26;9(3):e92703.
2.Wu WF, Sun LY, Pan XD, Yang SW, Wang LY*. Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia. PLoS One. 2014 Apr 10;9(4):e94697.
3.Li YH, Jiang L, Jia ZR, Xin W, Yang SW, Yang Q, Wang LY*. A meta-analysis of red yeast rice: an effective and relatively safe alternative approach for dyslipidemia. PLoS ONE, 2014, 9(6): e98611.
4.Zhang T, Wu WF, Liu Y, Wang QH, Wang LY*, Mi SH.Change in cholesterol absorption and synthesis markers in patients with coronary heart disease after combination therapy with simvastatin plus ezetimibe.Chin Med J (Engl). 2013，126(9):1618-1623
5.Wu WF, Wang QH, Zhang T, Mi SH, Liu Y, Wang LY*. Gas chromatography analysis of serum cholesterol synthesis and absorption markers used to predict the efficacy of simvastatin in patients with coronary heart disease. Clin Biochem. 2013;46(12):993-998.
6.Wang X, Li X, Zhang YB, Zhang F, Sun L, Lin J, Wang DM, Wang LY. Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci onchromosomes 3q25-26 and 21q22. PLoS One. 2011;6(10):e24838.
Contact: E-mail：wangluya@126.com, Phone: 010-64456436
