Upper Airway Dysfunction-Related Cardiovascular Diseases Laboratory
Yanwen Qin, Professor
Director of the Office of Beijing Institute of Heart, Lung and Blood Vessel Diseases
Director of the research laboratory of upper airway dysfunction-related cardiovascular diseases
一、Research Interests
The pathogenesis of lipid metabolism and atherosclerosis cardiovascular disease
二、Principle Investigator and Participate Project in 2020
Principle Investigator and Participate Project in 2020
1. “The role and mechanism of ANGPTL8/Betatrophin genetic variant in coronary artery disease” (01/2017-12/2020);
2. “The role and mechanism of angiopoietin-like protein 8 in vascular remodeling of hypertension” (01/2020-12/2023);
3. “The role and mechanism of angiopoietin-like protein 8 in abdominal aortic aneurysms forma tion” (01/2018-12/2021).
三、SCI papers published in 2020
1. Xiaolu Jiao, Yunyun Yang, Linyi Li, Huahui Yu, Yunxiao Yang, Juan Li, Yunhui Du, Jing Zhang, Chaowei Hu, Yanwen Qin*. Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE -/- mice. Atherosclerosis. 2020 Aug; 307:63-71.
2. Yunyun Yang, Xiaolu Jiao, Linyi Li, Chaowei Hu, Xiaoping Zhang, Lili Pan, Huahui Yu, Juan Li, Dong Chen, Jie Du, Yanwen Qin*. Increased Circulating Angiopoietin-Like Protein 8 Levels Are Associated with Thoracic Aortic Dissection and Higher Inflammatory Conditions. Cardiovasc Drugs Ther 2020 Feb;34(1):65-77.
3. Juan Li, Yunyun Yang, Xiaolu Jiao, Huahui Yu, Yunhui Du, Ming Zhang, Chaowei Hu, Yongx iang Wei*, Yanwen Qin*. The Clinical Role of Angiopoietin-Like Protein 3 in Evaluating Coro- nary Artery Disease in Patients with Obstructive Sleep Apnea. Cardiovasc Drugs Ther. 2020 Dec;34(6):773-780.
4. Chaowei Hu, Jing Li, Yunhui Du, Juan Li, Yunyun Yang, Yifan Jia, Lu Peng, Yanwen Qin*, Yongxiang Wei*. Impact of chronic intermittent hypoxia on the long non-coding RNA and mRNA expression profiles in myocardial infarction. J Cell Mol Med. 2020 Nov 20. doi:10.1111/
jcmm.16097. Online ahead of print.
5. Zhang J, Hu C, Jiao X, Yang Y, Li J, Yu H, Qin Y*, Wei Y*. Potential Role of mRNAs and Ln cRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis[J].Front Gen et. 2020,11(290).(IF=3.517)
四、Patent granted in 2020
Yongxiang Wei , Yanwen Qin, Linyi Li. Preventive and therapeutic effects of Salidroside on obstruc tive sleep apnea induced hypertension. ZL201710060824.1
Address
E-mail: qinyanwen@vip.126.com
Tel: 010-64456529
