研究方向：高血压病的基础与临床

主持及参与课题：

主持：（1）北京市自然科学基金《降压治疗对增殖抑制基因影响与机制的实验研究》（2010/01-2012/12）；（2）.国家自然科学基金《HSG在原发性高血压患者血管平滑肌细胞增殖中的作用》（2013/01-2013/12）；（3）.国家自然科学基金《线粒体融合基因2在原发性高血压患者血管平滑肌细胞中低表达的分子遗传机制研究》（2014/01-2017/12）；（4）北京市卫生系统高层次卫生技术人才培养计划（2014/12-2017/12）.

近五年发表SCI文章：

Wang Z, Niu Q, Peng X, Li M, Liu Y, Liu J, Wen S, Wei Y. Mitofusin 2 ameliorates aortic remodeling by suppressing ras/raf/ERK pathway and regulating mitochondrialfunction in vascular smooth muscle cells. Int J Cardiol. 2015;178:165-7. 

Wang Z, Liu Y, Liu J, Niu Q, Wen J, Wen S, Wu Z. A novel 5'-uncoding region -1248 A>G variation of mitofusin-2 gene is associated with hypertension in Chinese. Yonsei Med J. 2013;54(3):603-638.

Wang Z, Liu Y, Liu J, Liu K, Wen J, Wen S, Wu Z. HSG/Mfn2 gene polymorphism and essential hypertension: a case-control association study in Chinese. J Atheroscler Thromb. 2011;18(1):24-31.

Wang Z, Liu Y, Liu J, Liu K, Lou Y, Wen J, Niu Q, Wen S, Wu Z. E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population. BMC Med Genet. 2010 Aug 27;11:127. 

Wang Z, Peng X, Wei Y, Wen S. Neglect of several important indexes during the study of human essential hypertension. J Clin Hypertens (Greenwich). 2013;15(11):769-771. 

Zuoguang Wang, Xiaoyun Peng. Pathogenesis of essential hypertension: development of a 4-dimensional model. Hypothesis 2013;11(1): e3.

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