高血压研究室
刘洁琳 副研究员
研究方向:高血压的基础与临床研究
主持及参与课题:
作为骨干成员,参与国家863课题《原发性高血压病与增殖抑制基因(HSG)相关性的应用基础与临床研究》(2008/01-2010/12),北京自然科学基金面上项目《降压治疗对增殖抑制基因表达及功能的影响与机制研究》(2012./01-2014.12),北京自然科学基金重大项目课题《中国北京地区原发性高血压发病风险评估及早期预警体系研究》(2012/01-2015/12),国家自然科学基金面上项目《原发性高血压患者线粒体融合基因2启动子转录调控元件变异引发的转录调控异常与机制研究》(2014.1-2016.12)。
近五年发表SCI文章:
Liu J, Wang L, Liu Y, Wang Z, Li M, Zhang B, Wang H, Liu K, Wen S. The association between endothelial nitric oxide synthase gene G894T polymorphism and hypertension in Han Chinese: a case-control study and an updated meta-analysis. Ann Hum Biol. 2015 Mar;42(2):184-94.
Wang H , Liu J , Liu K, Liu Y, Wang Z, Lou Y, Niu Q, Gu W, Wang L, Li M, Zhu X, Wen S. β1-adrenoceptor gene Arg389Gly polymorphism and essential hypertension risk in general population: a meta-analysis. Mol Biol Rep. 2013;40(6): 4055-4063.
Gu W , Liu J , Niu Q, Wang H, Lou Y, Liu K, Wang L, Wang Z, Zhang J, Wen S.A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis. PLoS One. 2011 ; 6(12):e29489
Lou Y , Liu J , Li Y, Liu Y, Wang Z, Liu K, Wu H, Niu Q, Gu W, Guo Y, Li Z, Wen S,Association study of the β2-adrenergic receptor gene polymorphisms and hypertension in the Northern Han Chinese. PLoS One, 2011;6(4),e18590
Liu K , Liu J , Huang Y, Liu Y, Lou Y, Wang Z, Zhang H, Yan S, Li Z, Wen S,Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls. PLoS One.2010;5(9):e13057
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