Department of Hypertension Research
Zuoguang Wang, Associate Professor
Research Interests: Clinical and experimental research of essential hypertension.
Principal Investigator
· “Effect of antihypertensive treatment on hyperplasia suppressive gene: effects and mechanism”. Funded by the Beijing Natural Science Foundation. Support period: 01/2010–12/2012.
· “The effect of hyperplasia suppressive gene on VSMC proliferation and the potential mechanism”. Funded by the National Natural Science Foundation of China. Support period: 01/2013–12/2013.
· “Expression and mechanism of Mitofusin 2 affects VSMC and the potential mechanism”. Funded by the National Natural Science Foundation of China. Support period: 01/2014–12/2017.
· “Project of Beijing high level health technical talents of health system”. Support period: 1/2015-12/2017
SCI papers published in the past five years:
1. Wang Z, Niu Q, Peng X, Li M, Liu Y, Liu J, Wen S, Wei Y. Mitofusin 2 ameliorates aortic remodeling by suppressing ras/raf/ERK pathway and regulating mitochondrialfunction in vascular smooth muscle cells. Int J Cardiol. 2015;178:165-7.
2. Wang Z, Liu Y, Liu J, Niu Q, Wen J, Wen S, Wu Z. A novel 5'-uncoding region -1248 A>G variation of mitofusin-2 gene is associated with hypertension in Chinese. Yonsei Med J. 2013;54(3):603-638.
3. Wang Z, Liu Y, Liu J, Liu K, Wen J, Wen S, Wu Z. HSG/Mfn2 gene polymorphism and essential hypertension: a case-control association study in Chinese. J Atheroscler Thromb. 2011;18(1):24-31.
4. Wang Z, Liu Y, Liu J, Liu K, Lou Y, Wen J, Niu Q, Wen S, Wu Z. E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population. BMC Med Genet. 2010 Aug 27;11:127.
5. Wang Z, Peng X, Wei Y, Wen S. Neglect of several important indexes during the study of human essential hypertension. J Clin Hypertens (Greenwich). 2013;15(11):769-771.
6. Zuoguang Wang, Xiaoyun Peng. Pathogenesis of essential hypertension: development of a 4-dimensional model. Hypothesis 2013;11(1): e3.
Address：E-mail：wzg70@hotmail.com电话：010-64456462
