beiJing Institute Of Heart Lung And Blood Vessel Diseases

北京市心肺血管疾病研究所

Department of Hypertension Research

Jielin Liu, Associate Researcher

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Research Interests: Clinical and basic mechanisms of hypertension.

Participating Investigator

· “The pathophysiological role of the hyperplasia suppressor gene (HSG) on essential hypertension”. Funded by the Ministry of Science and Technology. Support period: 01/2008–12/2010.

· “The effects of antihypertensive therapy on the expression and function of hyperplasia suppressor gene”. Funded by the Beijing Natural Science Foundation. Support period: 01/2012–12/2014.

· “The study of establishment of the early warning system and risk assessment for essential hypertension in the Beijing area”. Funded by the Beijing Natural Science Foundation. Support period: 01/2012–12/2015.

· “The mechanism on abnormal transcriptional regulation caused by variants in 2nd promoter of hyperplasia suppressor gene in patients with essential hypertension”. Funded by the National Natural Science Foundation of China. Support period: 01/2014–12/2016.

SCI papers published in the past five years:

1. Liu J, Wang L, Liu Y, Wang Z, Li M, Zhang B, Wang H, Liu K, Wen S. The association between endothelial nitric oxide synthase gene G894T polymorphism and hypertension in Han Chinese: a case-control study and an updated meta-analysis. Ann Hum Biol. 2015 Mar;42(2):184-94.

2. Wang H , Liu J , Liu K, Liu Y, Wang Z, Lou Y, Niu Q, Gu W, Wang L, Li M, Zhu X, Wen S. β1-adrenoceptor gene Arg389Gly polymorphism and essential hypertension risk in general population: a meta-analysis. Mol Biol Rep, 2013;40(6), 4055-4063

3. Gu W , Liu J , Niu Q, Wang H, Lou Y, Liu K, Wang L, Wang Z, Zhang J, Wen S,A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis. PLoS One, 2011 ; 6(12),e29489

4. Lou Y , Liu J , Li Y, Liu Y, Wang Z, Liu K, Wu H, Niu Q, Gu W, Guo Y, Li Z, Wen S,Association study of the β2-adrenergic receptor gene polymorphisms and hypertension in the Northern Han Chinese. PLoS One, 2011;6(4),e18590

5. Liu K , Liu J , Huang Y, Liu Y, Lou Y, Wang Z, Zhang H, Yan S, Li Z, Wen S,Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls. PLoS One,2010;5(9),e13057

Address:E-mail:liu_jielin@aliyun.com Tel:010-64456462